WB;ELISA

Tyk 2 Monoclonal Antibody detects endogenous levels of Tyk 2 protein.

Purified recombinant fragment of Tyk 2 expressed in E. Coli.

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

tyrosine kinase 2(TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008],