产品详情
This antibody detects endogenous levels of Keap1 at Human, Mouse,Rat
免疫原详细信息
Synthesized peptide derived from human Keap1
相关试剂
PBS, pH7.4, 50% glycerol, 0.03%Proclin 300
背景
kelch like ECH associated protein 1(KEAP1) Homo sapiens This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008],
