产品详情
Phospho-EGFR (Y1172) Polyclonal Antibody detects endogenous levels of EGFR protein only when phosphorylated at Y1172.
免疫原详细信息
The antiserum was produced against synthesized peptide derived from human EGFR around the phosphorylation site of Tyr1172. AA range:1139-1188
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016],