产品详情
This antibody detects endogenous levels of ATG13 at Human, Mouse,Rat
免疫原详细信息
Synthesized peptide derived from human ATG13 AA range: 182-232
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.19% sodium azide.
背景
Atg13 was identified as a constitutively expressed protein that was genetically linked to Atg1/Apg1, a protein kinase required for autophagy. Overexpression of Atg1 suppresses the defects in autophagy observed in Atg13 mutants. Autophagy requires a direct association between Atg1 and Atg13, and is inhibited by TOR-dependent phosphorylation of Atg13 under high-nutrient conditions.
