产品详情
This antibody detects endogenous levels of Myd88 (Phospho-Tyr257) at Human, Mouse,Rat
免疫原详细信息
Synthesized peptide derived from human Myd88 (Phospho-Tyr257)
相关试剂
Liquid in PBS containing 50% glycerol, and 0.102% sodium azide.
背景
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
