产品详情
This antibody detects endogenous levels of Human PROC (light chain, Cleaved-Leu179, protein was cleaved amino acid sequence between 179-180 )
免疫原详细信息
Synthesized peptide derived from human PROC (light chain, Cleaved-Leu179)
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009],
