产品详情
Phospho-CREB-1 (S121) Polyclonal Antibody detects endogenous levels of CREB-1 protein only when phosphorylated at S121.
免疫原详细信息
The antiserum was produced against synthesized peptide derived from human CREB around the phosphorylation site of Ser121. AA range:91-140
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],
