产品详情
Phospho-Survivin (T117) Polyclonal Antibody detects endogenous levels of Survivin protein only when phosphorylated at T117.
免疫原详细信息
The antiserum was produced against synthesized peptide derived from human Survivin around the phosphorylation site of Thr117. AA range:86-135
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011],
