免疫原
Purified recombinant human GATA6 protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of GATA6 and does not cross-react with related proteins.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
其他名称
Gata binding factor 6;Gata binding protein 6;GATA-binding factor 6;Gata6;GATA6_HUMAN; Transcription factor Gata 6;Transcription factor GATA-6.
背景
This gene is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development. This gene is expressed during early embryogenesis and localizes to endo- and mesodermally derived cells during later embryogenesis and thereby plays an important role in gut, lung, and heart development. Mutations in this gene are associated with several congenital defects. [provided by RefSeq, Mar 2012],
功能
function:Thought to be important for regulating terminal differentiation and/or proliferation.,similarity:Contains 2 GATA-type zinc fingers.,tissue specificity:Expressed in heart, gut and gut-derived tissues.,
