基因名称(Gene Name)
CD99 MIC2 MIC2X MIC2Y
免疫原
Synthesized peptide derived from human CD99
特异性
The antibody can specifically recognize human CD99 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.101% sodium azide.
来源
Mouse, Monoclonal/IgG1, Kappa
稀释比例
IHC-p 1:100-500, WB 1:200-1000, IF 1:100-500
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
其他名称
CD99 antigen (12E7;E2 antigen;Protein MIC2;T-cell surface glycoprotein E2;CD antigen CD99)
背景
The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. [provided by RefSeq, Mar 2016],
功能
function:Involved in T-cell adhesion processes. It is involved in spontaneous rosette formation with erythrocytes.,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.,PTM:Extensively O-glycosylated.,similarity:Belongs to the CD99 family.,
