基因名称(Gene Name)
HMGB1 HMG1
蛋白名称
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
免疫原
Synthesized peptide derived from human HMGB1
特异性
This antibody detects endogenous levels of HMGB1 at Human, Mouse,Rat
组成
PBS, pH7.4, 50% glycerol, 0.03%Proclin 300
来源
Mouse,monoclonal:IgG1, Kappa
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
其他名称
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
背景
high mobility group box 1(HMGB1) Homo sapiens This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015],
功能
function:Binds preferentially single-stranded DNA and unwinds double stranded DNA.,similarity:Belongs to the HMGB family.,similarity:Contains 2 HMG box DNA-binding domains.,
