分子量(DA)
Calculated MW: 75 kDa; Observed MW: 68 kDa
免疫原
A synthesized peptide derived from human TGFBI
特异性
Affinity Chromatography
稀释比例
WB: 1/500-1/1000 IHC: 1/50-1/100
储存
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
背景
TGFBI is a RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. TGFBI plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. TGFBI is induced by transforming growth factor-beta and acts to inhibit cell adhesion.