应用范围
WB,IHC-P,ICC/IF,IP,FC
分子量（DA）
Calculated MW: 28 kDa; Observed MW: 28 kDa
免疫原
A synthesized peptide derived from human Caspase-14
稀释比例
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50 FC: 1/50-1/100
储存
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
其他名称
CASP14; Caspase-14; Caspase 14; MICE; CASP-14
背景
Caspases are a family of cysteine proteases that play an essential role in carrying out apoptosis. Caspase-14, also named MICE, is a unique member of the caspase family with restricted expression; it is found in embryonic tissues and adult skin. Caspase-14 is weakly processed into p18 and p11 subunits by caspase-8. May also be responsible for proteolytic processing of filaggrin during terminal differentiation of keratinocytes.
