分子量（DA）
Calculated MW:33kDa;Observed MW:46kDa
免疫原
A synthesized peptide derived from human PD-L1 (CD274)
稀释比例
WB: 1/500-1/1000 IHC: 1/100-1/200
储存
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
其他名称
B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; CD274;
背景
Programmed cell death ligand 1(CD274, or B7-H1, PD-L1), is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are key regulators of the adaptive immune response. CD274 is suggested a negative regulator of T and B cell, and play important role in mediating tolerance of lymphocytes to self-antigens.
