基因名称(Gene Name)
BSN KIAA0434 ZNF231
蛋白名称
Protein bassoon (Zinc finger protein 231)
免疫原
Synthesized peptide derived from human Bassoon/BSN
特异性
This antibody detects endogenous levels of Bassoon/BSNat Human, Mouse,Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02%sodiumazide.
来源
Polyclonal, Rabbit,IgG
纯化工艺
The antibody was affinity-purified from rabbit antiserumby
affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Scaffold protein of the presynaptic cytomatrix at the active zone (CAZ) whichisthe place in the synapse where neurotransmitter is released . After synthesis,participates in the formation of Golgi-derived membranous organellestermedPiccolo-Bassoon transport vesicles (PTVs) that are transported alongaxonstosites of nascent synaptic contacts . At the presynaptic active zone, regulatesthespatial organization of synaptic vesicle cluster, the protein complexesthat
execute membrane fusion and compensatory endocytosis (By similarity). Functions also in processes other than assembly such as the regulationof
specific presynaptic protein ubiquitination by interacting with SIAH1or theregulation of presynaptic autophagy by associating with ATG5 (By similarity).Mediates also synapse to nucleus communication leading to reconfigurationofgene expression by associating with the transcrip
