基因名称(Gene Name)
FAM65B C6orf32 DIFF48 KIAA0386 PL48
免疫原
Synthesized peptide derived from human FAM65B
特异性
This antibody detects endogenous levels of FAM65B at Human, Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization . Inhibits chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration . Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion (By similarity). Required for normal development of inner and outer hair cell stereocilia within the cochlea of the inner ear (By similarity). Plays a role for maintaining the structural organization of the basal domain of stereocilia (By similarity). Involved in mechanosensory hair cell function (By similarity). Required for normal hearing . ; [Isoform 2]: Acts as an inhibitor of the small GTPase RHOA . Plays a role in fetal mononuclear myoblast differentiation by promoting filopodia and myotube formation . Maintains naive T lymphocytes in a quiescent state .
