基因名称(Gene Name)
OSBPL2 KIAA0772 ORP2
蛋白名称
Oxysterol-binding protein-related protein 2 (ORP-2) (OSBP-related protein 2)
免疫原
Synthesized peptide derived from human OSBPL2
特异性
This antibody detects endogenous levels of OSBPL2 at Human, Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Intracellular transport protein that binds sterols and phospholipids and mediates lipid transport between intracellular compartments. Increases plasma membrane cholesterol levels and decreases phosphatidylinositol-4,5-bisphosphate levels in the cell membrane . Binds phosphoinositides, such as phosphatidylinositol-4,5-bisphosphate . Exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate . Binds cholesterol, dehydroergosterol, 22(R)-hydroxycholesterol and 25-hydroxycholesterol (in vitro) .
