背景
This gene encodes a member of the KN motif and ankyrin repeat domains (KANK) family of
proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The
encoded protein functions in the sequestration of steroid receptor coactivators and possibly
other proteins. Mutations in this gene are associated with impaired kidney podocyte function
and nephrotic syndrome, and keratoderma and woolly hair
