免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of
human PMM2 (NP_000294.1
纯化工艺
Affinity purification
储存
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
其他名称
PMI; CDG1; CDGS; PMI1; CDG1a; PMM 2; PMM2
背景
The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to
mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of
dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in
glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome
type I.
