免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of
human TRAF3IP2 (NP_671733.2).
纯化工艺
Affinity purification
储存
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
其他名称
ACT1; CIKS; C6orf2; C6orf4; C6orf5; C6orf6; CANDF8; PSORS13; TRAF3IP2
背景
This gene encodes a protein involved in regulating responses to cytokines by members of
the Rel/NF-kappaB transcription factor family. These factors play a central role in innate
immunity in response to pathogens, inflammatory signals and stress. This gene product
interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either IkappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative
transcripts encoding different isoforms have been identified. Another transcript, which does
not encode a protein and is transcribed in the opposite orientation, has been identified.
Overexpression of this transcript has been shown to reduce expression of at least one of the
protein encoding transcripts, suggesting it has a regulatory role in the expression of this
gene.
