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货号: YP-mAb-18526
促销价:

产品介绍

反应种属
Human,Mouse,Rat
应用范围
WB
抗体类型
单克隆抗体
基因名称(Gene Name)
蛋白名称
分子量(DA)
60kDa/58kDa
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 11-221 of PKM1/2(NP_001193728.1).
特异性
组成
来源
稀释比例
WB 1:500 - 1:1000
纯化工艺
Affinity purification
浓度
1 mg/ml
储存
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
其他名称
PK3; TCB; p58; OIP3; PKM2; CTHBP; THBP1; HEL-S-30; PKM1/2
背景
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.
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