免疫原
A synthetic peptide corresponding to a sequence within amino acids 368-467 of human IRF6
(O14896)
纯化工艺
Affinity purification
储存
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
其他名称
LPS; PIT; PPS; VWS; OFC6; PPS1; VWS1; IRF6
背景
This gene encodes a member of the interferon regulatory transcription factor (IRF) family.
Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain
and a less conserved C-terminal protein-binding domain. The encoded protein may be a
transcriptional activator. Mutations in this gene can cause van der Woude syndrome and
popliteal pterygium syndrome. Mutations in this gene are also associated with nonsyndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants
