免疫原
A synthetic peptide corresponding to a sequence within amino acids 545-644 of human
Cytokeratin 1 (KRT1) (P04264)
纯化工艺
Affinity purification
储存
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
其他名称
K1; CK1; EHK; AEI2; EHK1; EPPK; KRT1A; NEPPK; Cytokeratin 1 (KRT1)
背景
The protein encoded by this gene is a member of the keratin gene family. The type II
cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic
keratin chains coexpressed during differentiation of simple and stratified epithelial tissues.
This type II cytokeratin is specifically expressed in the spinous and granular layers of the
epidermis with family member KRT10 and mutations in these genes have been associated
with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in
a region of chromosome 12q12-q13.