产品详情
GCS-β-2 Polyclonal Antibody detects endogenous levels of GCS-β-2 protein.
免疫原详细信息
The antiserum was produced against synthesized peptide derived from human GCS-beta-2. AA range:53-102
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.