免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 849-1041
of human TLR8 (NP_619542.1).
纯化工艺
Affinity purification
储存
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
其他名称
CD288; IMD98; hTLR8; TLR8
背景
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which
plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs
are highly conserved from Drosophila to humans and share structural and functional
similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are
expressed on infectious agents, and mediate the production of cytokines necessary for the
development of effective immunity. The various TLRs exhibit different patterns of
expression. This gene is predominantly expressed in lung and peripheral blood leukocytes,
and lies in close proximity to another family member, TLR7, on chromosome X.
