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当前位置: 首页 > 产品中心 > 抗体 > 单克隆抗体 > Cyclin D1 Monoclonal Antibody
Cyclin D1 Monoclonal Antibody
  • 货号: YP-Ab-16555
  • 宿主: Monoclonal, Mouse
  • 反应性: Human
  • 应用: WB;ELISA
Cyclin D1 Monoclonal Antibody
Cyclin D1 Monoclonal Antibody
订购:YP-Ab-16555
规格:
  • 53ul
  • 100ul
价格:
¥1560.00
数量:
- +
测试应用
WB;ELISA
产品详情
Cyclin D1 Monoclonal Antibody detects endogenous levels of Cyclin D1 protein.
免疫原详细信息
Purified recombinant fragment of human Cyclin D1 expressed in E. Coli.
相关试剂
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
背景
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq, Jul 2008],
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