产品详情
The antibody can specifically recognize human INI-1 protein, including INI-1A and INI-1B. In western blotting of Hela and LnCap cell lysates, the antibody can label two bands with molecular weight of
免疫原详细信息
Synthesized peptide derived from human INI-1
相关试剂
PBS, pH7.2, 0.03% Porcolin 300, containing stabilizing protein
背景
The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015],
