产品详情
The antibody can specifically recognize human PCNA protein. In western blotting of Hela, A431 and HEK293 cell lysates, the antibody can label a 30 kDa band corresponding to PCNA.
免疫原详细信息
Synthesized peptide derived from human Proliferating Cell Nuclear Antigen
相关试剂
PBS, pH7.2, 0.03% Porcolin 300, containing stabilizing protein
背景
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008],
