产品详情
This antibody detects endogenous levels of human TGF β Receptor I. Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section
免疫原详细信息
Synthesized peptide derived from human TGF β Receptor I
相关试剂
Liquid in PBS containing, 0.5% BSA and 0.02% sodium azide.
背景
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],
