产品详情
Axl Monoclonal Antibody detects endogenous levels of Axl protein.
免疫原详细信息
Purified recombinant extracellular fragment of human Axl fused with hIgGFc tag expressed in HEK293 cell line.
相关试剂
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
背景
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],
