WB;ChIP;IF;FCM;ELISA

Flk-1 Monoclonal Antibody detects endogenous levels of Flk-1 protein.

Purified recombinant extracellular fragment of human Flk-1 (aa20-764) fused with hIgGFc tag expressed in HEK293 cells.

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009],