产品详情
This antibody detects endogenous levels of Rho A at Human, Mouse,Rat
免疫原详细信息
Synthesized peptide derived from human Rho A
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.50% sodium azide.
背景
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015],