产品详情
This antibody detects endogenous levels of Cofilin at Human, Mouse,Rat
免疫原详细信息
Synthesized peptide derived from human Cofilin
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.71% sodium azide.
背景
cofilin 1(CFL1) Homo sapiens The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004],
