产品详情
4E-BP1 Monoclonal Antibody detects endogenous levels of 4E-BP1 protein.
免疫原详细信息
Purified recombinant fragment of 4E-BP1 expressed in E. Coli.
相关试剂
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
背景
eukaryotic translation initiation factor 4E binding protein 1(EIF4EBP1) Homo sapiens This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008],
