产品详情
MPO Monoclonal Antibody detects endogenous levels of MPO protein.
免疫原详细信息
Purified recombinant fragment of MPO (aa1-193) expressed in E. Coli.
相关试剂
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
背景
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014],