WB;IHC;IF;ELISA

Troponin I-C Monoclonal Antibody detects endogenous levels of Troponin I-C protein.

Purified recombinant fragment of Troponin I-C expressed in E. Coli.

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008],