产品详情
Dynamin I Monoclonal Antibody detects endogenous levels of Dynamin I protein.
免疫原详细信息
Purified recombinant fragment of human Dynamin I expressed in E. Coli.
相关试剂
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
背景
dynamin 1(DNM1) Homo sapiens This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],