WB;ELISA

Integrin αL Polyclonal Antibody detects endogenous levels of Integrin αL protein.

The antiserum was produced against synthesized peptide derived from the Internal region of human ITGAL. AA range:171-220

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

integrin subunit alpha L(ITGAL) Homo sapiens ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],