产品详情
BubR1 Polyclonal Antibody detects endogenous levels of BubR1 protein.
免疫原详细信息
The antiserum was produced against synthesized peptide derived from human BUB1B. AA range:341-390
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008],