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当前位置: 首页 > 产品中心 > 抗体 > 多克隆抗体 > ATM Rabbit Polyclonal Antibody
ATM Rabbit Polyclonal Antibody
  • 货号: YP-Ab-14286
  • 宿主: Polyclonal, Rabbit,IgG
  • 反应性: Human;Rat;Mouse
  • 应用: IHC;IF
ATM Rabbit Polyclonal Antibody
ATM Rabbit Polyclonal Antibody
ATM Rabbit Polyclonal Antibody
订购:YP-Ab-14286
规格:
  • 53ul
  • 100ul
价格:
¥1340.00
数量:
- +
测试应用
IHC;IF
产品详情
ATM protein detects endogenous levels of ATM
免疫原详细信息
Recombinant Protein of ATM of ATM
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010],
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