产品详情
Phospho-p70 S6 kinase α (S447) Polyclonal Antibody detects endogenous levels of p70 S6 kinase α protein only when phosphorylated at S447.
免疫原详细信息
The antiserum was produced against synthesized peptide derived from human p70 S6 Kinase around the phosphorylation site of Ser424. AA range:414-463
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
ribosomal protein S6 kinase B1(RPS6KB1) Homo sapiens This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013],
