产品详情
Phospho-PAKγ (S192) Polyclonal Antibody detects endogenous levels of PAKγ protein only when phosphorylated at S192.
免疫原详细信息
The antiserum was produced against synthesized peptide derived from human PAK2 around the phosphorylation site of Ser192. AA range:158-207
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008],
