产品详情
Phospho-SPAK (S325) Polyclonal Antibody detects endogenous levels of SPAK protein only when phosphorylated at S325.
免疫原详细信息
The antiserum was produced against synthesized peptide derived from human STK39 around the phosphorylation site of Ser325. AA range:291-340
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008],
