产品详情
This antibody detects endogenous levels of CSFR (Phospho Tyr921) Rabbit pAb at Human, Mouse,Rat
免疫原详细信息
Synthesized peptide derived from human CSFR (Phospho Tyr921)
相关试剂
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
背景
colony stimulating factor 1 receptor(CSF1R) Homo sapiens The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],
