产品详情
This antibody detects endogenous levels of Human,Mouse,Rat Dab1 (Phospho Tyr220)
免疫原详细信息
Synthesized peptide derived from human Dab1 (Phospho Tyr220)
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
domain:The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.,function:Adapter molecule functioning in neural development. May regulate SIAH1 activity.,PTM:Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.,similarity:Contains 1 PID domain.,subunit:Associates with the SH2 domains of SRC, FYN and ABL. Interacts with DAB2IP and SIAH1 (By similarity). Interacts with LRP1.,
