产品详情
This antibody detects endogenous levels of STING (Phospho-Ser366) at Human, Mouse,Rat
免疫原详细信息
Synthesized peptide derived from human STING (Phospho-Ser366)
相关试剂
Liquid in PBS containing 50% glycerol, and 0.111% sodium azide.
背景
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014],