产品详情
This antibody detects endogenous levels of ZAK (Phospho-Ser165) at Human, Mouse,Rat
免疫原详细信息
Synthesized peptide derived from human ZAK (Phospho-Ser165)
相关试剂
Liquid in PBS containing 50% glycerol, and 0.152% sodium azide.
背景
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
