产品详情
This antibody detects endogenous levels of EIF6 (Phospho-Ser235) at Human, Mouse,Rat
免疫原详细信息
Synthesized peptide derived from human EIF6 (Phospho-Ser235)
相关试剂
Liquid in PBS containing 50% glycerol, and 0.155% sodium azide.
背景
Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012],
