产品详情
This antibody detects endogenous levels of TIE1 (Phospho-Tyr1117) at Human, Mouse,Rat
免疫原详细信息
Synthesized peptide derived from human TIE1 (Phospho-Tyr1117)
相关试剂
Liquid in PBS containing 50% glycerol, and 0.158% sodium azide.
背景
This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],
