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当前位置: 首页 > 产品中心 > 抗体 > 多克隆抗体 > BCL-10 (Phospho-Ser138) rabbit pAb
BCL-10 (Phospho-Ser138) rabbit pAb
  • 货号: YP-Ab-10509
  • 宿主: Polyclonal, Rabbit,IgG
  • 反应性: Human; Mouse;Rat
  • 应用: WB
BCL-10 (Phospho-Ser138) rabbit pAb
BCL-10 (Phospho-Ser138) rabbit pAb
BCL-10 (Phospho-Ser138) rabbit pAb
订购:YP-Ab-10509
规格:
  • 53ul
  • 100ul
价格:
¥1340.00
数量:
- +
测试应用
WB
产品详情
This antibody detects endogenous levels of BCL-10 (Phospho-Ser138) at Human, Mouse,Rat
免疫原详细信息
Synthesized peptide derived from human BCL-10 (Phospho-Ser138)
相关试剂
Liquid in PBS containing 50% glycerol, and 0.165% sodium azide.
背景
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
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